| brand name | generic name | drug class or drug category | general use |
| Z-Pak | azithromycin 250MG (6 tabs) | macrolide antibiotic; antibacterial | bacterial infections |
| Zaditor | ketotifen (ophthalmic) | antihistamine; antiallergic | allergic conjunctivitis; allergic eyes; itchy eyes |
| Zanaflex | tizanidine | muscle relaxant | to treat muscle spasms associated with multiple sclerosis or spinal injury |
| Zanosar | streptozocin | antineoplastic; alkylating agent | to treat various cancers (pancreas cancer) |
| Zantac | ranitidine | histamine H2 antagonist; H2 blocker | ulcers; GERD; heartburn (acid indigestion and sour stomach) |
| Zarontin | ethosuximide (oral) | anticonvulsant | to treat absence or petit mal seizures |
| Zaroxolyn | metolazone | thiazide-like diuretic (water pill) | high blood pressure; fluid accumulation |
| Zavesca | miglustat | substrate reduction therapy | to treat Gaucher disease |
| Zazole | terconazole | antifungal | to treat vaginal yeast infections |
| Zebeta | bisoprolol | beta blocker | high blood pressure (hypertension) |
| Zegerid | omeprazole (oral) | proton pump inhibitor (PPI) | ulcers; GERD; heartburn |
| Zelnorm | tegaserod (oral) | serotonin agonist; 5-HT4 receptor agonist | irritable bowel syndrome (IBS) |
| Zemplar | paricalcitol | vitamin D analogs | to lower parathyroid hormone (PTH) levels |
| Zenapax | daclizumab | monoclonal antibody; immuno suppressant | to prevent rejection of kidney transplants |
| Zerit | stavudine | antiviral; reverse transcriptase inhibitor | human immunodeficiency virus (HIV) |
| Zestoretic | lisinopril/hydrochlorothiazide (oral) | antihypertensive | hypertension; congestive heart failure |
| Zestril | lisinopril (oral) | ACE inhibitor; antihypertensive | hypertension (high blood pressure) |
| Zetia | ezetimibe (oral) | lipid lowering agent; antihyperlipidemic; antihypercholesterolemic | to lower levels of total cholesterol and LDL (bad) cholesterol in the blood |
| Ziac | bisoprolol/hydrochlorothiazide | antihypertensive | hypertension (high blood pressure) |
| Ziagen | abacavir | antiviral | human immunodeficiency virus (HIV) |
| Ziana gel | clindamycin/tretinoin | combination of antibiotic and a retinoid | for the topical treatment of acne vulgaris in patients 12 years or older |
| Zinecard | dexrazoxane | chelating agent; cardioprotective agent | to lessen heart problems due to cancer treatment |
| Zinotic | chloroxylenol/pramoxine/zinc | nonantibiotic antimicrobial agent | to treat some ear infections and to relieve ear pain and itching |
| Zithromax | azithromycin | macrolide antibiotic; antibacterial | bacterial infections |
| Zithromax Z-Pak | azithromycin | macrolide antibiotic; antibacterial | bacterial infections |
| Zmax | azithromycin (oral suspension) | macrolide antibiotic; antibacterial | bacterial infections |
| Zocor | simvastatin | HMG-CoA reductase inhibitor; statins; lipid lowering agent | to lower the LDL (bad cholesterol) and triglycerides in the blood, and to raise the HDL (good cholesterol) |
| Zofran | ondansetron | serotonin 5-HT3 receptor antagonist; antiemetic and antinauseant | to prevent nausea and vomiting due to cancer chemotherapy or radiation therapy; prevention of postoperative nausea and vomiting |
| Zofran ODT | ondansetron | serotonin 5-HT3 receptor antagonist; antiemetic and antinauseant | to prevent nausea and vomiting due to cancer chemotherapy or radiation therapy; prevention of postoperative nausea and vomiting |
| Zoloft | sertraline | SSRI (antidepressant) | depression; SAD; OCD; PTSD; PMDD |
| Zometa | zoledronic acid (injection) | bisphosphonate; antihypercalcemic | to treat hypercalcemia of malignancy; to treat multiple myeloma and bone metastases of solid tumors |
| Zomig | zolmitriptan | selective 5-HT agonist; antimigraine | migraine headaches |
| Zomig-ZMT | zolmitriptan | selective 5-HT agonist; antimigraine | migraine headaches |
| Zonalon | doxepin (topical) | antipruritic; anti-itch | to relieve itching due to certain skin conditions |
| Zonegran | zonisamide (oral) | anticonvulsant | to treat seizures in adults with epilepsy |
| Zostavax | zoster vaccine live | virus vaccine | it is a subcutaneous injection to prevent herpes zoster (shingles) in individuals 60 years of age and older |
| Zosyn | piperacillin/tazobactam | penicillin antibiotic; antibacterial | bacterial infections |
| Zotane HC aqueous | pramoxine, hydrocortisone, and chloroxylenol | anesthetic, steroid, and antibacterial combination | to treat some ear infections and to relieve ear pain and itching |
| Zovia | ethinyl estradiol/ethynodiol diacetate | female hormone (contraceptive) | to prevent pregnancy |
| Zovirax | acyclovir | antiviral; antiherpes | genital herpes; shingles; cold sores; herpes skin infections |
| Zovirax cream 2g or 5g | acyclovir | antiviral; antiherpes | to treat cold sores |
| Zovirax ointment 15g | acyclovir | antiviral; antiherpes | genital herpes; skin herpes infections |
| ZPak | azithromycin 250MG (6 tabs) | macrolide antibiotic; antibacterial | bacterial infections |
| Zyban | bupropion SR | smoking cessation aid; anti-smoking | to stop smoking |
| Zyflo CR | zileuton | antiasthmatic; leukotriene inhibitor | for the prophylaxis and chronic treatment of asthma in adults and children |
| Zylet | loteprednol/tobramycin | cortico-steroid and antibiotic | to treat certain eye inflammation |
| Zyloprim | allopurinol (oral) | antigout; antihyperuricemic | to treat gout; to lower uric acid levels |
| Zymar | gatifloxacin (ophthalmic) | quinolone antibiotic; antibacterial | bacterial infections of the eyes |
| Zyprexa | olanzapine | antipsychotic | mental disorders (schizophrenia, bipolar disorder) |
| Zyprexa Zydis | olanzapine | antipsychotic | mental disorders (schizophrenia, bipolar disorder) |
| Zyrtec | cetirizine | antihistamine; H1 receptor blocker | allergies |
| Zyrtec-D | cetirizine/pseudoephedrine | antihistaminic decongestant | nasal and non-nasal allergies |
| Zyvox | linezolid | oxazolidinone antibiotic; antibacterial | bacterial infections |
| brand name | generic name | drug class or drug category | general use |